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Thesis

Clinical and neuroimaging biomarkers of early and prodromal Parkinson's disease

Abstract:

The degeneration of the substantia nigra starts many years before the motor symptoms first emerge and the diagnosis of Parkinson’s disease (PD) can finally be made. Identification of patients at the early, prodromal, stage would provide insight into the earliest pathological pathways in PD and allow the targeted use of novel neuroprotective agents, slowing or even halting the progression of the disease. Patients with idiopathic REM sleep behaviour disorder (RBD) have been found to have a much...

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Division:
MSD
Department:
Clinical Neurosciences
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Supervisor
ORCID:
0000-0001-6382-5841
Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Supervisor
ORCID:
0000-0001-6111-8318
More from this funder
Name:
Parkinson's UK
Funder identifier:
http://dx.doi.org/10.13039/501100000304
Funding agency for:
Rolinski, M
Programme:
Monument Trust Discovery Award
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Name:
OUCAGS and Oxford NIHR BRC
Funding agency for:
Rolinski, M
Programme:
Clinical Research Training Fellowship
More from this funder
Name:
Dementias and Neurodegenerative Diseases Research Network (DeNDRoN)
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Deposit date:
2023-04-27

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