Thesis
Development of image-based method for the quantitative assessment of cartilage damage from CT as a biomarker in osteoarthritis
- Abstract:
-
Preclinical studies, like those for drug development, require quantitative methods to assess osteoarthritis (OA). In OA, cartilage damage and subchondral bone deformations are critical indicators. Therefore, this thesis introduces and validates two innovative frameworks for automated OA assessment, centering on the image analysis of cartilages and subchondral bones.
Cartilage is typically invisible in Computed Tomography (CT) scans without an injected contrast agent. The first fram...
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Authors
Contributors
+ Vincent, T
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- NDORMS
- Sub department:
- Kennedy Institute for Rheumatology
- Role:
- Supervisor
+ Lim, N
- Role:
- Supervisor
+ Papiez, B
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- NDM
- Sub department:
- Big Data Institute
- Role:
- Supervisor
- ORCID:
- 0000-0002-8432-2511
+ Kamnitsas, K
- Institution:
- University of Oxford
- Division:
- MPLS
- Department:
- Engineering Science
- Role:
- Examiner
+ Dell'accio, F
- Role:
- Examiner
+ Kennedy Trust for Rheumatology Research
More from this funder
- Grant:
- AZT00050-AZ04
- Programme:
- Kennedy Trust Prize Studentship
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2025-01-20
Terms of use
- Copyright holder:
- Zheng, J-Q
- Copyright date:
- 2024
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