Thesis
Plasma proteomic landscape and patient stratification in response to severe infection
- Abstract:
-
Rationale: A dysregulated host response to infection can cause life-threatening organ dysfunction, presenting as the clinical syndrome of sepsis. Sepsis is an unmet global health challenge, with substantial clinical and molecular heterogeneity hindering the development of targeted therapies. Subphenotypes in sepsis have been identified at the clinical and molecular levels, especially using the leukocyte transcriptome. Due to the limited throughput of proteome profiling, th...
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Authors
Contributors
+ Knight, J
Institution:
University of Oxford
Role:
Supervisor
ORCID:
0000-0002-0377-5536
+ Burnham, K
Institution:
Wellcome Sanger Institute
Role:
Supervisor
ORCID:
0000-0001-8680-2933
+ Kessler, B
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Examiner
+ Shankar-Hari, M
Role:
Examiner
Funding
+ University of Oxford
More from this funder
Funder identifier:
https://ror.org/052gg0110
Funding agency for:
Mi, Y
Programme:
Covid-19 scholarship extensions fund
+ China Scholarship Council and University of Oxford
More from this funder
Funding agency for:
Mi, Y
Programme:
China Scholarship Council - University of Oxford Scholarship
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- DOI:
Item Description
- Language:
-
English
- Keywords:
- Subjects:
- Deposit date:
-
2023-12-14
Related Items
Terms of use
- Copyright holder:
- Mi, Y
- Copyright date:
- 2022
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