- Abstract:
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There are major gaps in our understanding of the evolution of microRNA (miRNA) genes and how this relates to evolutionary changes in metazoan development. miRNAs function as trans-acting post-transcriptional modulators of gene expression. They are implicated in the canalization of development and the consequent provision of evolvability. Here I present data and analyses on miRNA evolution in insects and mammals, both on a phylogenetic scale as well as at the level of individual mi...
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Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
- Department:
- Department of Zoology, University of Oxford
- Role:
- Supervisor
- Funding agency for:
- Project
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Copyright date:
- 2015
Thesis
Conservation and innovation - the evolution of the metazoan microRNA landscape and its contribution to reproduction and development
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Authors
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+ Peter Holland
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+ Agency for Science, Technology and Research, Singapore
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