Thesis
Conservation and innovation - the evolution of the metazoan microRNA landscape and its contribution to reproduction and development
- Abstract:
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There are major gaps in our understanding of the evolution of microRNA (miRNA) genes and how this relates to evolutionary changes in metazoan development. miRNAs function as trans-acting post-transcriptional modulators of gene expression. They are implicated in the canalization of development and the consequent provision of evolvability. Here I present data and analyses on miRNA evolution in insects and mammals, both on a phylogenetic scale as well as at the level of individual mi...
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Authors
Contributors
+ Holland, P
Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Supervisor
Funding
Agency for Science, Technology and Research, Singapore
More from this funder
Elizabeth Hannah Jenkinson Fund
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
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uuid:aabb8d6b-f92a-4b0f-94a5-0a2e6d7f7963
- Deposit date:
- 2016-03-14
Terms of use
- Copyright holder:
- Quah, S
- Copyright date:
- 2015
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