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Thesis

Metabolism studies in breast cancer

Abstract:

Metabolic reprogramming has emerged as a common phenotype of cancers. Otto Warburg in 1920s observed that cancer cells consume higher amounts of glucose for their metabolism producing high levels of lactate even in normal oxygen conditions, this has been termed as the Warburg effect. In breast cancer, this seemingly wasteful metabolism of glucose is mirrored by a similarly inefficient metabolism of glutamine.

Glutamine is the most abundant amino acid in plasma and it constitutes an...

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Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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