Testing the neurocognitive model of antidepressant treatment

Thesis

The neurocognitive model of antidepressant treatment action states that antidepressants work by producing relatively immediate positive shifts in emotional processing, which translate into clinical improvement with time. Short-term or even acute doses of antidepressants can, for example, increase memory for positive self-referent words or decrease amygdala activation to fearful faces, and these early changes correlate with later clinical improvement. However, there are a number of ways in whi...

Expand abstract

Authors: Warren, M

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: emotion; neuroimaging; mood disorders; antidepressants; neuroticism
• Subjects: Neurosciences