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Thesis

Structural studies of the Type IX secretion system inner membrane complex

Abstract:

The Type IX Secretion System (T9SS) is a protein transport system found exclusively in the Bacteroidetes phylum of Gram-negative bacteria. The T9SS transports folded substrates across the outer membrane, including virulence factors of human pathogens, polysaccharide utilisation enzymes of environmental bacteria, and cell-surface adhesin molecules involved in Bacteroidetes gliding motility

The inner membrane proteins GldL and GldM use the proton-motive force to energise both the T9S...

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Division:
MSD
Department:
Doctoral Training Centre - MSD
Role:
Author
ORCID:
0000-0001-9009-9726

Contributors

Role:
Supervisor
ORCID:
0000-0001-9287-8053
Role:
Supervisor
ORCID:
0000-0001-9685-4067
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Name:
Wellcome Trust
Funder identifier:
http://dx.doi.org/10.13039/100010269
Grant:
102164/Z/13/Z
Programme:
Cellular Structural Biology DTC
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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