Thesis
Defining the molecular mechanisms of control of the TMEM16A channel by GPCR receptors
- Abstract:
-
Background: The scope of this project is to study the mechanisms underlying the regulation of the vascular transmembrane protein TMEM16A, a Ca2+-gated Cl- (CaCC) channel. The physiological and pharmacological stimuli studied include: (i) activation of G protein-coupled receptors (GPCRs) by physiological agonists, (ii) changes in the histological properties of the vessel wall, and (iii) intracellular pathways and possible binding partners that the channel may share with other ... Expand abstract
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Authors
Contributors
+ Tammaro, P
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Pharmacology
- Role:
- Supervisor
- ORCID:
- 0000-0002-6183-8187
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Deposit date:
-
2026-02-16
- ARK identifier:
Terms of use
- Copyright holder:
- Catherine Seoyoun Choi
- Copyright date:
- 2025
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