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Thesis

Assessing the role of optimal information size in systematic reviews

Abstract:

Background and objectives

The concept of optimum information size (OIS) was first proposed by Pogue and Yusuf in a 1997 article published in Controlled clinical trials, as “the minimum amount of information required in the collective literature for reliable conclusions about an intervention to be reached”. OIS estimates, which are mainly based on standard sample size calculations, are influenced by several variables, including the control event rate (CER), effect size (ES) an...

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Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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