Thesis
Transcriptomic profiling of non-cardiomyocytes during both early and late stages of adverse remodelling in hypertrophic cardiomyopathy (HCM)
- Abstract:
-
Background: Familial hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease characterised by unexplained ventricular hypertrophy, myocyte disarray, and fibrosis. Although the biophysical mechanisms by which gene variants in sarcomeric proteins disrupt cardiomyocyte function are largely understood, the cellular and molecular pathways leading to the complex, variable, and adverse remodelling of the non-myocyte compartment are not fully characterised. Understanding t... Expand abstract
Actions
Authors
Contributors
+ Watkins, H
- Role:
- Supervisor
+ Redwood, C
- Role:
- Supervisor
+ Dendrou, C
- Role:
- Supervisor
+ Wang, YJ
- Role:
- Supervisor
+ University of Oxford
More from this funder
- Funder identifier:
- https://ror.org/052gg0110
- Grant:
- SFF2122_CSCUO_ 1284663
- Programme:
- China Scholarship Council - University of Oxford Scholarship
+ China Scholarship Council
More from this funder
- Funder identifier:
- https://ror.org/04atp4p48
- Grant:
- SFF2122_CSCUO_ 1284663
- Programme:
- China Scholarship Council - University of Oxford Scholarship
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Deposit date:
-
2025-09-10
Terms of use
- Copyright holder:
- Siwei Deng
- Copyright date:
- 2025
If you are the owner of this record, you can report an update to it here: Report update to this record