Thesis
Hypoxia and the tumour microenvironment : an analysis of breast cancer heterogeneity
- Abstract:
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Breast cancer, the most prevalent cancer worldwide, boasts a high 5-year survival rate exceeding 90% with early detection. Despite this, the disease's intrinsic heterogeneity and therapeutic resistance remain formidable challenges in clinical management, particularly in advanced stages. Among the four primary subtypes identified by hormone receptor expression—luminal A, luminal B, HER2-enriched, and triple-negative breast cancer (TNBC)—TNBC stands out for its aggressive metastatic behavior an...
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- Files:
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(Preview, Dissemination version, pdf, 38.2MB, Terms of use)
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Authors
Contributors
+ Buffa, F
- Role:
- Supervisor
+ Harris, A
- Role:
- Supervisor
+ Barberis, A
- Role:
- Supervisor
- ORCID:
- 0000-0002-6718-855X
+ Gedara, J
- Role:
- Supervisor
+ Mohammed bin Rashid Al Maktoum Knowledge Foundation
More from this funder
- Funding agency for:
- Barberis, A
- Programme:
- Oxford-Sheikh Mohammed bin Rashid Al Maktoum (MBRF) Graduate Scholarship
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Pubs id:
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2350277
- Local pid:
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pubs:2350277
- Deposit date:
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2025-11-11
- ARK identifier:
Terms of use
- Copyright holder:
- Badran Elshenawy
- Copyright date:
- 2024
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