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Thesis

Identification and characterisation of candidate monoclonal antibody Ebolavirus therapeutics

Abstract:

Multiple species of Ebolaviruses can cause outbreaks of devastating disease with high mortality. The 2014 outbreak in West Africa, focused attention on efforts to develop effective vaccines and therapies to save lives. Since then, vaccines and first generation therapies have been developed and approved for use. The only therapies to have shown any efficacy in human clinical trials are monoclonal antibodies (mAbs) targeting the Glycoprotein (GP) on the virus surface. However, they are limit...

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Division:
MSD
Department:
NDM
Role:
Author

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Role:
Supervisor
ORCID:
0000-0002-9415-1357
Role:
Supervisor
Role:
Supervisor
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Name:
Medical Research Council
Programme:
MRC iCASE
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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