- Abstract:
-
Radiotherapy is the use of ionising radiation to induce localised DNA damage to cancerous tissues, leading to cell death and disease control. In order to maximise tumour growth control and to limit damage of the healthy surrounding tissues and the consequent side effects for the patient, molecular determinants of tumour radioresistance are investigated as potential clinical targets.
A high-throughput siRNA colony formation assay screen in HeLa cervical carcinoma cells previously pub...
Expand abstract - Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
-
uuid:a2b05e51-7f21-433f-8d28-51ac1a72a503
- Language:
- English
- Keywords:
- Subjects:
- Copyright holder:
- Pirovano, GM
- Copyright date:
- 2016
Thesis
TOPK as a novel determinant of radiosensitivity
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