Thesis
Development of (Z)-alkenylsilane coupling methodology and application towards the synthesis of incednine
- Abstract:
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This thesis describes the development of methods for the synthesis of incednam, the aglycon of incednine, via Hiyama cross-coupling. An early chapter discusses the efforts to improve upon previous efforts to access major building blocks. This is followed by a chapter focusing on the development of a novel strategy to access more reactive dimethyl alkenylsiloxanes and their applications. Finally, this new strategy is applied to the synthesis and different approaches to assemble incednam are explored.
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
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uuid:a28281e4-47e2-435e-a303-32047913e3e1
- Deposit date:
- 2018-05-06
Terms of use
- Copyright holder:
- Kuper, C
- Copyright date:
- 2017
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