Thesis
Regulation and function of innate-like T cells
- Abstract:
-
KLRB1, encoding for CD161, is one of the most favourable prognostic pan-cancer genes. It is expressed by NK- and T-cell subsets, particularly by innate-like T cells such as MAIT and γδT cells. CD161-expressing T-cell subsets share a transcriptional and functional phenotype, including the ability to be activated by cytokines in a T-cell receptor-independent manner, similar to NK cells. The regulation and function of CD161-expressing cells as well as their role in cancer is not fully understood...
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Authors
Contributors
+ Klenerman, P
Role:
Supervisor
+ Buffa, F
Role:
Supervisor
+ Willberg, C
Role:
Supervisor
Funding
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Deposit date:
- 2022-01-08
Related Items
Terms of use
- Copyright holder:
- Hagel, JP
- Copyright date:
- 2021
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