Thesis icon

Thesis

Glucosamine Synthetase in the Human Gastrointestinal Mucosa in Health and Disease

Abstract:

Glucosamine synthetase (L-glutamine-D-fructose-6-phosphate amino-transferase, EC.2.6.1.16) is the cytoplasmic enzyme which catalyses the synthesis of glucosamine-6-phosphate from fructose-6-phosphate and glutamine. It is a rate-limiting step in the biosynthesis of UDP-N-acetyl-glucosamine and probably also of gastrointestinal mucus, which is glycoprotein in composition. Glycoproteins consist of a protein backbone on which are assembled complex carbohydrate side-chains. The first sugar to b...

Expand abstract
Peer review status:
Peer reviewed

Actions


Access Document


Files:

Authors


More by this author
Department:
University of Oxford
Role:
Author
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Source identifiers:
601870435
UUID:
uuid:9c231317-8cbe-4ac4-bf7a-575bfac8c2d9
Local pid:
polonsky:7:38
Deposit date:
2017-10-05

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP