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Prospective observational cohort study of the association between thromboelastometry, coagulation and platelet parameters and bleeding in patients with haematological malignancies‐ The ATHENA study

Abstract:

Previous studies have shown that total platelet count (TPC) inadequately predicts bleeding in thrombocytopenic patients with haematological malignancies. This prospective cohort study evaluated whether rotational thromboelastometry (ROTEM), coagulation or other platelet parameters were more strongly associated with bleeding than TPC. Adults treated at two UK haematology centres for haematological malignancy were enrolled if they had thrombocytopenia (TPC ≤ 50 × 109/l) at beginning of, or duri...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/bjh.12928

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
Publisher:
Wiley
Journal:
British Journal of Haematology More from this journal
Issue:
4
Publication date:
2014-05-05
Acceptance date:
2014-03-24
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Pmid:
24797282
Keywords:
Pubs id:
pubs:480667
UUID:
uuid:9b197d2f-d781-47bc-b033-9fbdbf0984f6
Local pid:
pubs:480667
Source identifiers:
480667
Deposit date:
2017-09-04

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