Design and development of influenza neuraminidase nanoparticle vaccine

Thesis

Lay abstract
Influenza continues to cause significant illness and death worldwide, with existing vaccines offering only limited protection. While these vaccines focus on a surface protein called haemagglutinin (HA), another key protein, neuraminidase (NA), has been less extensively studied as a vaccine target. NA facilitates viral spread by releasing the virus from infected cells, and NA monoclonal antibodies have been found to be protective and broadly reactive. In this ... Expand abstract

Authors: Wei, L

• DOI: 10.5287/ora-vyajvemz5
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English