Thesis
Development and preclinical analysis of lipopolysaccharide-based glycoconjugate vaccine candidates against Coxiella burnetti
- Abstract:
-
Q fever is a zoonosis caused by the Gram-negative bacterium Coxiella burnetii. Currently, there is only one licensed human vaccine for Q fever, but its high level of reactogenicity necessitates the urgent need for developing a safer and efficacious alternative. Prior research has highlighted the utility of anti-C. burnetii phase I (smooth form) lipopolysaccharide (LPS) IgG antibodies in conferring protection against Q fever. Drawing on this foundation, this thesis describ...
Expand abstract
Actions
Authors
Contributors
+ Pollard, A
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Paediatrics
- Role:
- Supervisor
- ORCID:
- 0000-0001-7361-719X
+ Rollier Weissenburger, C
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Paediatrics
- Role:
- Supervisor
- ORCID:
- 0000-0002-9712-8080
+ O'Connor, D
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Paediatrics
- Role:
- Supervisor
- ORCID:
- 0000-0002-6902-9886
+ Kim, Y
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Paediatrics
- Role:
- Supervisor
- ORCID:
- 0000-0003-2847-9407
+ Chelysheva, I
- Institution:
- University of Oxford
- Division:
- MSD
- Department:
- Paediatrics
- Role:
- Supervisor
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
-
English
- Keywords:
- Subjects:
- Pubs id:
-
1994189
- Local pid:
-
pubs:1994189
- Deposit date:
-
2024-05-02
- ARK identifier:
Terms of use
- Copyright holder:
- Zhu, H
- Copyright date:
- 2024
If you are the owner of this record, you can report an update to it here: Report update to this record