Journal article

6-deoxyhexoses from L-rhamnose in the search for inducers of the rhamnose operon: Synergy of chemistry and biotechnology

Abstract:: In the search for alternative non-metabolizable inducers in the L-rhamnose promoter system, the synthesis of fifteen 6-deoxyhexoses from L-rhamnose demonstrates the value of synergy between biotechnology and chemistry. The readily available 2,3-acetonide of rhamnonolactone allows inversion of configuration at C4 and/or C5 of rhamnose to give 6-deoxy-D-allose, 6-deoxy-D-gulose and 6-deoxy-L-talose. Highly crystalline 3,5-benzylidene rhamnonolactone gives easy access to L-quinovose [6-deoxy-L-g...
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Publication status:: Published

Peer review status:: Peer reviewed

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APA Style

Liu, Z., Wormald, M., Yoshihara, A., Kelly, C., Heap, J., Marqvorsen, M., Jenkinson, S., Otero, J., Estévez, A., Kato, A., Fleet, G., Estévez, R., & Izumori, K. (2016). 6-deoxyhexoses from L-rhamnose in the search for inducers of the rhamnose operon: Synergy of chemistry and biotechnology. Chemistry - A European Journal, 22(35), 12557–12565.

MLA Style

Liu, Z., et al. “6-Deoxyhexoses from L-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology.” Chemistry - A European Journal, vol. 22, no. 35, Wiley, 2016, pp. 12557–65.

Chicago Style

Liu, Z, M Wormald, A Yoshihara, C Kelly, J Heap, M Marqvorsen, S Jenkinson, et al. 2016. “6-Deoxyhexoses from L-Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology.” Chemistry - A European Journal 22 (35): 12557–65.
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Files:: Fleet et al, 6-deoxyhexoses from L-rhamnose in the search for ...

(Preview, Accepted manuscript, pdf, 1.4MB, Terms of use)

Publisher copy:: 10.1002/chem.201602482

Authors

+ Liu, Z More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Biochemistry

Role:

Author

+ Wormald, M More by this author

Institution:

University of Oxford

Division:

MSD

Department:

Biochemistry

Role:

Author

+ Yoshihara, A More by this author

Role:

Author

+ Kelly, C More by this author

Role:

Author

+ Heap, J More by this author

Role:

Author

More authors...

Funding

+ Xunta de Galicia More from this funder

Grant:

GRC2014/040

+ Biotechnology and Biological Sciences Research Council More from this funder

Grant:

BB/M011321/1

+ Leverhulme Trust More from this funder

Funding agency for:

Fleet, G

Bibliographic Details

Publisher:: Wiley
Journal:: Chemistry - A European Journal More from this journal
Volume:: 22
Issue:: 35
Pages:: 12557–12565
Publication date:: 2016-07-01
Acceptance date:: 2016-06-21
DOI:: 10.1002/chem.201602482

Item Description

Keywords:: rhamnonolactone

rare sugar

6-deoxyhexose

rhamnose operon
Pubs id:: pubs:631798
UUID:: uuid:9a03fc97-01ae-4c72-af6a-9393e5116b48
Local pid:: pubs:631798
Source identifiers:: 631798
Deposit date:: 2016-07-04

Terms of use

Copyright holder:: WILEY-VCH Verlag GmbH and Co
Copyright date:: 2016
Notes:: © 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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