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Thesis

Mechanisms underlying apathy in health and Parkinson's disease

Abstract:

Apathy or lack of motivation is increasingly recognized to be a major factor affecting quality of life and prognosis in many neurological conditions. It is particularly prevalent in Parkinson’s disease, impacting on every disease stage, including de novo cases, and has been reported to affect up to 70% of cases. Despite the pervasiveness of apathy, challenges remain in its detection, clinical assessment and treatment. Several lines of evidence have implicated fronto-striatal reward related...

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Department:
University of Oxford, Nuffield Department of Clinical Neurosciences

Contributors

Department:
University of Oxford, Nuffield Department of Clinical Neurosciences
Role:
Examiner
Department:
University of Oxford, Nuffield Department of Clinical Neurosciences
Role:
Supervisor
Department:
University of Oxford, Nuffield Department of Clinical Neurosciences
Role:
Supervisor
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Grant:
104364/Z/14/Z
Funding agency for:
Kinan Muhammed
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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