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Thesis

Glycine receptor antibodies: pathogenic mechanisms and clinical corrlates

Abstract:

Glycine receptor antibodies have been identified in a few patients with progressive encephalomyelitis with rigidity and myoclonus (PERM), a highly disabling disorder characterised by rigidity, spasm and brainstem symptomatology. The clinical characteristics of patients with glycine receptor antibodies have not yet been fully described and it is not clear whether GlyR-Abs are pathogenic or just an epiphenomenon.

This study examined the clinical features and immunotherapy responses of...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Research group:
Neuroimmunology
Oxford college:
St Hugh's College
Role:
Author

Contributors

Division:
MSD
Department:
Clinical Neurosciences
Role:
Supervisor
More from this funder
Name:
Colfuturo, Colciencias
Funding agency for:
Carvajal González, A
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:8d9e92c6-6c02-4d62-b3fc-086d8dd297a5
Local pid:
ora:10484
Deposit date:
2015-03-11

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