Thesis
Development and application of methods for qualitative and quantitative analysis of amino acid post-translational modifications using liquid chromatography coupled to mass spectrometry
- Abstract:
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The 2-oxoglutarate and ferrous ion dependent oxygenases are a super family of enzymes that are involved in a wide range of biological processes regulated trough the mechanism of post-translational modification (PTM). Such biological processes include hypoxia sensing (through regulating HIF transcription), fatty acid metabolism (through carnitine production), transcriptional regulation (through demethylation of histones), and collagen structure formation (through proline and lysine hydroxyl...
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(Preview, Dissemination version, bin, 12.4MB, Terms of use)
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Authors
Contributors
+ McCullagh, JSO
- Division:
- MPLS
- Department:
- History Faculty
- Sub department:
- Archaeology Research Lab
- Role:
- Supervisor
- Publication date:
- 2014
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
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English
- Keywords:
- Subjects:
- UUID:
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uuid:8c737f3c-b24d-437d-abac-bada61351173
- Local pid:
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ora:8515
- Deposit date:
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2014-06-04
- ARK identifier:
Terms of use
- Copyright holder:
- Loik, N
- Copyright date:
- 2013
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