- Abstract:
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The extracellular matrix (ECM) is a complex network of molecules secreted by cells, which is essential for providing structural support and facilitating cell processes including adhesion, migration and survival. Tenascin-C is an immunomodulatory ECM protein that exhibits limited expression in healthy tissues, but is transiently elevated at sites of tissue injury, and is persistently expressed in chronic inflammatory diseases and tumours. Alternative splicing of 9 of tenascin-C's fibronecti...
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- Department:
- Kennedy Institute of Rheumatology, University of Oxford
- Role:
- Supervisor
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
- English
- Keywords:
- Subjects:
- Copyright date:
- 2018
Thesis
Investigating cell lineage specific biosynthesis of tenascin-C during inflammation
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+ Kim Midwood
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