Thesis

Investigating the pathogenic effects of antibodies against the VGKC-complex and N-methyl-D-aspartate receptor in CNS disorders

Abstract:: Over the last few years, antibody-mediated disorders of the central nervous system (CNS) have been a rapidly expanding field in neurology. The antibodies bind to extracellular domains of proteins expressed in the CNS and impair neuronal function. Patients with limbic encephalitis, Morvan’s syndrome have antibodies that bind to the voltage gated potassium channel (VGKC)-complex proteins, LGI1 and CASPR2, while patients with antibodies to the NMDAR have more complex encephalopathies. Clinica...
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APA Style

Pettingill, P. M. (2013). Investigating the pathogenic effects of antibodies against the VGKC-complex and N-methyl-D-aspartate receptor in CNS disorders [PhD thesis]. University of Oxford.

MLA Style

Pettingill, P. M. Investigating the Pathogenic Effects of Antibodies against the VGKC-Complex and N-Methyl-D-Aspartate Receptor in CNS Disorders. University of Oxford, 2013.

Chicago Style

Pettingill, PM. 2013. “Investigating the Pathogenic Effects of Antibodies against the VGKC-Complex and N-Methyl-D-Aspartate Receptor in CNS Disorders.” PhD thesis, University of Oxford.
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Files:: Pettingill_2013_Investigating_the_pathogenic.pdf

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Authors

+ Pettingill, PM More by this author

Institution:: University of Oxford
Division:: MSD
Research group:: Nuffield Department of Clinical Neurosciences
Oxford college:: St Cross College
Role:: Author

Contributors

Division:: MSD
Department:: Clinical Neurosciences
Role:: Supervisor

+ Medical Research Council More from this funder

Funding agency for:: Pettingill, PM

Publication date:: 2013
Type of award:: DPhil
Level of award:: Doctoral
Awarding institution:: University of Oxford

Language:: English
Keywords:: Neurology

Immunology
Subjects:: Neurology

Immunology
UUID:: uuid:8c117bc1-5e6e-4adc-8e5b-eefc2deff380
Local pid:: ora:8201
Deposit date:: 2014-03-14

Terms of use

Copyright holder:: Pettingill, PM
Copyright date:: 2013

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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