Thesis
Role of MukBEF in Escherichia coli chromosome organization
- Abstract:
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In E. coli cells, spatial chromosome organization reflects the genetic map, with the origin located at mid-cell and left and right replichores in either cell half. In contrast to the eukaryotic cell cycle, chromosome segregation occurs progressively as replication proceeds. The highly conserved SMC complex, MukBEF, plays a central role in chromosome organization and segregation, with null mutants having temperature sensitive growth and mispositioned chromosomal regions. However, d...
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Funding
+ Department of Biochemistry, Clarendon award
More from this funder
Funding agency for:
Badrinarayanan, A
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:8abe7a64-cf7d-433a-9165-0ca2ced915b6
- Deposit date:
- 2016-11-15
Terms of use
- Copyright holder:
- Badrinarayanan, A
- Copyright date:
- 2012
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