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Thesis

Respiratory immunisation and mucosal immunity against influenza

Abstract:

Influenza A virus (IAV) is a considerable threat to human and animal health. Current immunisation strategies rely primarily on inducing strain-specific neutralising antibodies with a limited breadth of protection. Increasing evidence indicates the importance of local immune responses and tissue resident memory T cells (TRM) for broad protection against respiratory infections, however, a vaccine that can be safely delivered to the lung is yet to be approved. In addition, there is little inf...

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Division:
MSD
Department:
RDM
Role:
Author

Contributors

Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Supervisor
Role:
Supervisor
Role:
Supervisor


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Keywords:
Subjects:
Deposit date:
2022-06-23
ARK identifier:

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