Thesis
Incorporation of trehalose analogues into Mycobacterium Tuberculosis: antigen 85 and probes of bacterial infection
- Abstract:
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Diagnoses of tuberculosis, 'TB,' currently rely upon non-specific techniques such as X-ray exams and acid-fast microscopy. Improved diagnostics would preferably consider specific bacterial processes to provide real-time readouts of disease burden and response to chemotherapy. This dissertation presents the cell-wall incorporation of trehalose analogues (fluorescent and radioactive) by the mycobacterial antigen 85 enzymes as a novel method to label the causative bacteria of TB, Mycobac...
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Authors
Contributors
+ Davis, B
Division:
MPLS
Department:
Chemistry
Role:
Supervisor
+ Barry, C
Division:
MPLS
Department:
Chemistry
Role:
Supervisor
Funding
+ Rhodes Trust; NIH Oxford Cambridge Scholars Program
More from this funder
Funding agency for:
Backus, K
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:882d8560-c0d3-471b-a896-224a6b22a0f0
- Local pid:
- ora:11632
- Deposit date:
- 2015-06-11
Terms of use
- Copyright holder:
- Backus, K
- Copyright date:
- 2012
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