Thesis
Simulating large DNA nanostructures with a coarse-grained model
- Abstract:
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In this thesis we investigate the self-assembly and structural properties of DNA origamis, which are large-scale DNA nanostructures comprising thousands of DNA base pairs, using the coarse-grained model of DNA called oxDNA.
We use simulations of oxDNA, with both a "brute-force" approach and with a rareevent method, to probe how the origamis self-assemble from single strands of DNA in solution. With the brute-force approach we are able to simulate the complete assembly of a smal...
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Funding
Engineering & Physical Sciences Research Council
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- UUID:
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uuid:86b2d03e-3cad-423c-8db0-3d56c65ccc20
- Deposit date:
- 2016-02-29
Terms of use
- Copyright holder:
- Snodin, B
- Copyright date:
- 2016
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