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Acquired alpha thalassaemia in myelodysplastic syndrome

Abstract:

Alpha thalassaemia occurs when there is reduced production of the alpha globin compared to beta globin chains of haemoglobin. Although this almost always results from inherited defects in the alpha globin genes, over the past 50 years, a rare acquired form of alpha thalassaemia (AT) has been reported in patients with myelodysplastic syndrome (MDS); the so-called ATMDS syndrome. With one exception, in these individuals there appear to be no mutations in the alpha globin genes or their regul...

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Division:
MSD
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Weatherall Insti. of Molecular Medicine
Role:
Supervisor
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Funding agency for:
Cheong, P
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:847c8f7f-c0d9-4272-8cac-f1c0c0ec4719
Deposit date:
2019-01-16

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