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Thesis

Phenotypic models of T cell activation

Abstract:

T cells are important immune cells that initiate and regulate immune responses to cell surface antigens. The productive binding of T cell receptors (TCRs) to cell surface antigens initiates a signal transduction cascade within the T cell that results in T cell effector functions. It is established that the dose of antigen and the binding parameters between TCRs and antigen determines the functional response of the T cell. Although much progress has been made to identify the molecules ...

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Division:
MPLS
Department:
Doctoral Training Centre - MPLS
Role:
Author

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Supervisor
Role:
Supervisor
Engineering & Physical Sciences Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
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UUID:
uuid:83a14d45-484b-4d20-a31f-74063f49adce
Deposit date:
2016-02-26

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