Thesis
The nicotinic acid receptor in human adipose tissue
- Abstract:
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Nicotinic acid (NA) has been clinically used for over 50 years to regulate lipid plasma levels. It is the only drug in current clinical use that significantly raises HDL cholesterol and reduces inflammatory markers. However, mechanistic understanding into its wide range of actions remains unclear. The recent identification of the Gi-coupled protein receptor HCAR2, for which NA is a potent agonist, provides intriguing insight due to its anti-lipolytic action and restricted, yet specific, ex...
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(Preview, pdf, 16.0MB, Terms of use)
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Authors
+ Rhodes Trust; European Foundation for the Study of Diabetes
More from this funder
- Funding agency for:
- Chamas, L
- Publication date:
- 2013
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- Language:
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English
- Keywords:
- Subjects:
- UUID:
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uuid:82650691-be95-4cf7-a3cd-e0821062f49d
- Local pid:
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ora:8415
- Deposit date:
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2014-05-12
- ARK identifier:
Terms of use
- Copyright holder:
- Liliane Chamas
- Copyright date:
- 2013
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