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Thesis

Modelling the impact of heterogeneity in tumour composition on the response to fractionated radiotherapy

Abstract:

Current protocols for delivering radiotherapy are based primarily on tumour stage and nodal and metastases (TNM) status, even though it is well known that tumours and their microenvironments are highly heterogeneous. Mathematical models have the potential to inform protocol selection on a more patient-specific basis. However such applications require early prediction of tumour response and, thus, calibration of the model parameters from pre-treatment data which is typically limited to two ...

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Division:
MPLS
Department:
Mathematical Institute
Department:
Mathematical Institute
Role:
Author

Contributors

Department:
Mathematical Institute
Role:
Supervisor
Department:
Mathematical Institute
Role:
Supervisor

DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Keywords:
UUID:
uuid:7c9ef972-2094-4f0d-a860-6a31fd75679e
Deposit date:
2019-10-17
ARK identifier:

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