Thesis icon

Thesis

Functional analysis of mutations in isocitrate dehydrogenase involved in gliomagenesis

Abstract:

The main subject of my thesis is the investigation of mechanisms of glioma tumorigenesis associated with the recently identified mutations in isocitrate dehydrogenase. Gliomas account for 80% of primary brain cancers. They represent a diverse group of tumours, and are graded from I-IV based on histopathological features. Whilst grade I tumours may be curable with surgery alone, grade II and III gliomas inevitably progress to glioblastoma multiforme (GBM), which is highly resistant to curre...

Expand abstract

Actions

  • Cite

  • Print

Access Document

Files:

Authors

More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Research group:
Tomlinson
Oxford college:
Green Templeton College
Role:
Author

Contributors

Role:
Supervisor

Publication date:
2014
DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK

Language:
English
Keywords:
UUID:
uuid:79f06454-d126-4fb6-9aa7-6ccf835763d2
Local pid:
ora:11442
Deposit date:
2015-05-14
ARK identifier:

Terms of use

Views and Downloads





If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP