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Thesis

The crosstalk of ferroptosis and autophagy regulated by MAFF

Abstract:

Ferroptosis is an iron-dependent form of regulated cell death caused by an accumulation of lipid-based reactive oxygen species. The more aggressive subtypes of breast cancer have been reported to show an increased susceptibility, and therefore, triggering ferroptotic cell death is a strategy that could be employed to improve the sensitivity to chemotherapy and radiotherapy.

In our previous study, expression of the transcription factor MAFF was identified to be significantly eleva...

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor
ORCID:
0000-0001-7916-7978
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor


DOI:
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford


Language:
English
Deposit date:
2024-06-02
ARK identifier:

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