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Thesis

Assessment of anti-merozoite antibody function in the context of blood-stage malaria vaccine development

Abstract:

In regions endemic for malaria, natural exposure results in an acquired immunity which protects individuals from severe disease. However, no vaccine against the blood-stage of malaria, against which naturally-acquired immunity is targeted, currently exists that is capable of emulating, or out-performing, natural protection. To rationally direct the next generation of blood-stage malaria vaccine development, a greater understanding of the immunological mechanisms involved in clinical protec...

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Department:
Nuffield Department of Clinical Medicine

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Supervisor
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Type of award:
DPhil
Awarding institution:
University of Oxford
Language:
English
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