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Thesis

Multi-omics studies of the molecular architecture of age, ageing and age-related disorders

Abstract:

Background:

Ageing is a complex and heterogeneous process influenced by genetic, environmental, and lifestyle factors, with notable differences between sexes. High-throughput omics technologies, such as proteomics and metabolomics, provide new opportunities to quantify and understand the molecular underpinnings of ageing and the largest ageing contributor-smoking.

Methods:

This thesis applied machine learning approaches to large-scale ...

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Population Health
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Supervisor
ORCID:
0000-0001-9276-2720
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Supervisor


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Keywords:
Subjects:
Deposit date:
2025-10-17

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