Thesis
Control of expression of human snRNA genes
- Abstract:
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In humans, protein-coding genes and most small nuclear (sn)RNA genes are transcribed by RNA polymerase II (pol II).The carboxy-terminal domain (CTD) of the largest subunit of pol II possesses multiple heptapetide repeats of the consensus Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Phosphorylation of Ser2, Ser5 and Ser7 mediates the recruitment of transcription and RNA processing factors during the transcription cycle. There are notable differences between snRNA genes and protein-coding genes in te...
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(bin, 3.0MB, Terms of use)
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Authors
- Publication date:
- 2013
- DOI:
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
- Language:
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English
- Keywords:
- Subjects:
- UUID:
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uuid:7192b270-deda-4501-b0ad-68134f3b3a36
- Local pid:
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ora:12218
- Deposit date:
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2015-09-07
- ARK identifier:
Terms of use
- Copyright holder:
- Justyna Zaborowska
- Copyright date:
- 2013
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