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Thesis

Deconvolution of small molecule pleiotropic effects during immunomodulation

Abstract:

Ischaemic heart disease is one of the leading causes of death worldwide, and is rapidly growing in prevalence. Despite improvements in response and treatment times, individuals who suffer from cardiac ischaemic injury are at risk of developing chronic heart failure. The development of regenerative therapeutics which harness endogenous recovery mechanisms to optimise repair of the injured heart after ischaemic injury are highly desired. One emerging mechanism via modulation of the immune re...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy and Genetics
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy and Genetics
Role:
Supervisor
ORCID:
0000-0002-9862-7332


More from this funder
Funder identifier:
https://ror.org/029chgv08
Grant:
218514/Z/19/Z
Programme:
Chemistry in Cells: New Technologies to Probe Complex Biology & Medicine


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford


Language:
English
Deposit date:
2026-02-18
ARK identifier:

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