Thesis
Identifying biophysical determinants of virus-cell fusion through live-cell imaging
- Abstract:
-
The biophysical properties of both enveloped virus and cell membranes must be favourable for successful fusion and entry of the virus into its host. Characterising these properties in cells and virions is critical for understanding and manipulating target cell susceptibility to infection, as well as blocking infection by cell-autonomous antiviral proteins. To characterise such properties, we developed imaging assays multiplexing genetically-encoded biosensors concomitant with single virus ...
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Authors
Contributors
+ Compton, A
Institution:
National Cancer Institute
Role:
Supervisor
+ Compeer, E
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Supervisor
+ Padilla Parra, S
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Research group:
Cellular Imaging
Role:
Supervisor
+ Bowden, T
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Structural Biology
Role:
Examiner
+ Neil, S
Institution:
King's College London
Role:
Examiner
Funding
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Deposit date:
- 2021-04-26
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Terms of use
- Copyright holder:
- Coomer, CA
- Copyright date:
- 2021
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