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Macaque parvocellular mediodorsal thalamus: dissociable contributions to learning and adaptive decision‐making

Abstract:

Distributed brain networks govern adaptive decision‐making, new learning and rapid updating of information. However, the functional contribution of the rhesus macaque monkey parvocellular nucleus of the mediodorsal thalamus (MDpc) in these key higher cognitive processes remains unknown. This study investigated the impact of MDpc damage in cognition. Preoperatively, animals were trained on an object‐in‐place scene discrimination task that assesses rapid learning of novel information within eac...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1111/ejn.14078

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Institution:
University of Oxford
Division:
Medical Sciences Division
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Experimental Psychology
Oxford college:
Magdalen College
Role:
Author
ORCID:
0000-0001-8996-1067
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Funding agency for:
Ouhaz, Z
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Funding agency for:
Mitchell, AS
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Funding agency for:
Mitchell, AS
Publisher:
John Wiley & Sons Ltd Publisher's website
Journal:
European Journal of Neuroscience Journal website
Volume:
49
Issue:
8
Pages:
1041-1054
Publication date:
2018-08-16
Acceptance date:
2018-07-04
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
Pubs id:
pubs:891039
URN:
uri:6cd33985-b770-4638-9555-6f218e552ffd
UUID:
uuid:6cd33985-b770-4638-9555-6f218e552ffd
Local pid:
pubs:891039

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