Thesis
Exploring the mechanisms responsible for energetic dysfunction within the type 2 diabetic heart
- Abstract:
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Cardiovascular disease accounts for 70% of mortality within type 2 diabetic (T2D) patients. Energetic dysfunction is apparent within the T2D heart, presenting as a decreased phosphocreatine/adenosine triphosphate (PCr/ATP) ratio. This pathophysiology is an independent predictor for mortality risk within the setting of heart failure. While most clinical measurements of cardiac PCr/ATP ratios within T2D patients display a reduced PCr/ATP ratio some disagree, showing no defect. Emerging work ...
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Actions
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- UUID:
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uuid:6bc35fdf-4d66-4863-b3ab-5c707accbc59
- Deposit date:
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2020-01-11
Terms of use
- Copyright holder:
- Kerr, M
- Copyright date:
- 2019
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