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Thesis

Disentangling genetics of endometriosis and adenomyosis with a focus on Eastern Mediterranean populations

Abstract:

Endometriosis and adenomyosis are distinct yet frequently comorbid gynaecological conditions characterised by the ectopic presence of endometrial like tissue. While both are oestrogen-dependent and share overlapping clinical manifestations, accumulating evidence supports separate pathogenic mechanisms. Endometriosis has a well-established heritable component and 42 genome-wide significant loci identified to date through large-scale metaanalyses. In contrast, no genome-wide association study (...

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Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Supervisor
ORCID:
0000-0002-0275-9905
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Supervisor


DOI:
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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