- Abstract:
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Growth in the use of mass spectrometry as an analytical tool for studying protein structure and functionality has posed questions regarding correlation of native structures and observed gas-phase conformations for proteins. This thesis explores the relationship between the solution-phase and gas-phase structures of soluble proteins, and investigates the effect of the lipid environment on membrane proteins.
To assess gas-phase structure, ion-mobility mass spectrometry was used to mea...
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- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
- English
- Copyright date:
- 2017
Thesis
Probing environmental effects on gas-phase protein structure
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