Thesis
Probing environmental effects on gas-phase protein structure
- Abstract:
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Growth in the use of mass spectrometry as an analytical tool for studying protein structure and functionality has posed questions regarding correlation of native structures and observed gas-phase conformations for proteins. This thesis explores the relationship between the solution-phase and gas-phase structures of soluble proteins, and investigates the effect of the lipid environment on membrane proteins.
To assess gas-phase structure, ion-mobility mass spectrometry was used to mea...
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- UUID:
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uuid:6856e99f-c802-4b96-ba7c-8fc98456f6a0
- Deposit date:
- 2018-07-03
Terms of use
- Copyright holder:
- Hewitt, D
- Copyright date:
- 2017
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