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Thesis

Investigation of expression quantitative trait loci and regulatory genetic variants in primary human immune cells

Abstract:

The post human genome sequence era has begun to explore various aspects of the functional genome in relation to disease including gene expression, genetic variation and epigenetics. The genetic determinants of common and complex phenotypes are difficult to resolve even though their heritability is recognised. Recent genome-wide association studies (GWAS) for common diseases has identified many new disease susceptibility associated loci. These loci often lie in non-coding regions of the gen...

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Institution:
University of Oxford
Oxford college:
St Cross College
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Wellcome Trust Centre for Human Genetics

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Role:
Supervisor
Role:
Supervisor
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:67d0c1e8-c6f1-4ca7-a311-52f20b79128b
Local pid:
ora:10692

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