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Synthetic studies using chiral stabilised azomethine ylids

Abstract:

The work described herein is concerned with the [3+2] dipolar cycloaddition of amino acid derived azomethine ylids. Such cycloadditions are a highly efficient technique for the construction of proline derivatives, and may potentially be employed in other areas of asymmetric synthesis.

Chapter 1 commences with a brief review of natural and synthetic, proline containing, molecules. Approaches to the synthesis of the proline moiety are described, focusing on previously developed method...

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Peer review status:
Peer reviewed

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Department:
University of Oxford
Role:
Author
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Source identifiers:
603833598
UUID:
uuid:64d5745b-e6ef-4a77-8abe-b01f1c627e8f
Local pid:
polonsky:3:10
Deposit date:
2017-10-04

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