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Investigating small non-coding RNA regulating the hallmarks of cancer

Abstract:

Non-coding RNA are increasingly being implicated as key regulators of the human transcriptome, and are thought to play important roles in the pathogenesis and progression of cancer. Understanding how non-coding RNA, specifically microRNA (miRNA) and circular RNA (circRNA), contribute to cancer is an area of significant clinical interest.

In this work, I utilise existing large genomic datasets, generated from the Cancer Genome Atlas and Metabric projects to gain insight into the...

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Andrew Dhawan More by this author

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Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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