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Thesis

Characterisation of macrophage infiltration into solid tumours via image analysis and computational modelling

Abstract:

Macrophages are innate immune cells that play a key role in conditions as diverse as wound healing, atherosclerosis and cancer. In cancer, macrophages may be characterised as anti-tumour, promoting a wider immune response and phagocytosing tumour cells, or as pro-tumour, suppressing the immune response and promoting blood vessel growth and metastasis. The spatial distribution of macrophages inside a tumour correlates with patient prognosis and treatment response, and is hypothesised to b...

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Department:
Mathematical Institute
Role:
Author

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Department:
Mathematical Institute
Role:
Supervisor
Department:
Mathematical Institute
Role:
Supervisor
Department:
IBME, University of Oxford
Role:
Supervisor
Department:
Roche Pharma Research and Early Development
Role:
Supervisor
Department:
Roche Pharma Research and Early Development
Role:
Supervisor
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Funding agency for:
Joshua Bull
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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