Thesis icon

Thesis

Characterisation of macrophage infiltration into solid tumours via image analysis and computational modelling

Abstract:

Macrophages are innate immune cells that play a key role in conditions as diverse as wound healing, atherosclerosis and cancer. In cancer, macrophages may be characterised as anti-tumour, promoting a wider immune response and phagocytosing tumour cells, or as pro-tumour, suppressing the immune response and promoting blood vessel growth and metastasis. The spatial distribution of macrophages inside a tumour correlates with patient prognosis and treatment response, and is hypothesised to b...

Expand abstract

Actions


Access Document


Authors


More by this author
Division:
MPLS
Department:
Mathematical Institute
Department:
Mathematical Institute
Role:
Author

Contributors

Department:
Mathematical Institute
Role:
Supervisor
Department:
Mathematical Institute
Role:
Supervisor
Department:
IBME, University of Oxford
Role:
Supervisor
Department:
Roche Pharma Research and Early Development
Role:
Supervisor
Department:
Roche Pharma Research and Early Development
Role:
Supervisor
More from this funder
Name:
EPSRC/MRC Centre for Doctoral Training in Systems Approaches to Biomedical Science
Funding agency for:
Bull, J
Grant:
EP/G037280/1
More from this funder
Name:
Medical Research Council
Funding agency for:
Bull, J
More from this funder
Name:
Engineering & Physical Sciences Research Council
Funding agency for:
Bull, J
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP