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Intracellular signalling, gene induction and histone modifications in Drosophila melanogaster

Abstract:

In eukaryotes, histone H3 residues at the promoter and transcriptional start site of immediate early genes are phosphorylated at serine 10, a process mediated by histone kinases downstream of the p38 and ERK cascades. However, this phosphorylation event has not yet been investigated in Drosophila melanogaster, and the existence of an inducible histone kinase is uncertain.

To identify the kinases involved in the nucleosomal response in Drosophila, I first investigat...

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Oxford college:
St Catherine's College
Role:
Author

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Division:
MSD
Department:
Biochemistry
Role:
Supervisor
Publication date:
2015
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:62f2a994-0c9e-4bd0-b204-2fd5d1fa66a4
Local pid:
ora:9725
Deposit date:
2015-01-13

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