Synthesis of oxygen containing functionalities: use of the acyloin and metathesis reactions in organic chemistry

Thesis

1. In the first part of this thesis, the concept of a tether based intramolecular crossed-acyloin reaction mediated by heterogeneous lithium/ 4,4'-di-tert-butylbiphenyl (Li/DBB) reducing conditions was examined. The objective of the project was to accomplish an intramolecular crossed-acyloin reaction, by employing non-symmetric di-esters, linked with a suitable tether (diol) between the two acyl functionalities.

Chapter 1: Introduction – Acyloin Condensation

The conc...

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Authors: Jahanshahi Esfahani, A

• Publication date: 2012
• DOI: 10.5287/ora-br4wyyvnx
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: regioselective crossed acyloin; organic chemistry; reduction; ring opening metathesis; sharpless asymmetric epoxidation
• Subjects: Organic chemistry